Neutrophil mobilization into peritoneal fluid.
نویسنده
چکیده
منابع مشابه
Anti-Inflammatory Effects of IL-27 in Zymosan-Induced Peritonitis: Inhibition of Neutrophil Recruitment Partially Explained by Impaired Mobilization from Bone Marrow and Reduced Chemokine Levels
Rapid activation of the innate immune system is critical for an efficient host response to invading pathogens. However, the inflammatory reaction has to be strictly controlled to minimize harmful immunopathology. A number of mediators including the cytokine interleukin-27 (IL-27) appear to be responsible for limitation and resolution of inflammation. Despite increasing knowledge of its suppress...
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LTHOUGH it is true that adrenal glucocorticoids have found wide clinical application as effective anti-inflammatory agents, they must be used with caution since they can also cause an increased susceptibility to infection. The present investigation was prompted by a desire to gain additional information regarding the role of adrenal steroids in relation to the extravascular migration of polymor...
متن کاملNeutrophil mobilization from the bone marrow during polymicrobial sepsis is dependent on CXCL12 signaling.
Neutrophils are essential for successful host eradication of bacterial pathogens and for survival to polymicrobial sepsis. During inflammation, the bone marrow provides a large reserve of neutrophils that are released into the peripheral circulation where they traverse to sites of infection. Although neutrophils are essential for survival, few studies have investigated the mechanisms responsibl...
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Background: Chemokines, proteins that operate within the body's immune system, play numerous roles in menstruation, bacterial infection, implantation of embryos, and the maintenance of early pregnancy. They are also strongly related to the pathogenesis of endometriosis. Materials and Methods: This is review article that were indentifical by computer search of MEDLINE (1984- 2013). Results:...
متن کاملUrokinase-type plasminogen activator receptor plays a role in neutrophil migration during lipopolysaccharide-induced peritoneal inflammation but not during Escherichia coli-induced peritonitis.
BACKGROUND Urokinase-type plasminogen activator receptor (uPAR) is expressed on many different cells, including leukocytes. uPAR has been implicated to play a role in neutrophil migration to sites of inflammation. METHODS To determine the role that uPAR plays in neutrophil recruitment in response to bacterial products or intact bacteria, uPAR gene-deficient (uPAR(-/-)) and wild-type (wt) mice...
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ورودعنوان ژورنال:
- Blood
دوره 16 شماره
صفحات -
تاریخ انتشار 1960